Age Dependent Differences in Collagen Alignment of Glutaraldehyde Fixed Bovine Pericardium
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چکیده
منابع مشابه
Age Dependent Differences in Collagen Alignment of Glutaraldehyde Fixed Bovine Pericardium
Bovine pericardium is used for heart valve leaflet replacement where the strength and thinness are critical properties. Pericardium from neonatal animals (4-7 days old) is advantageously thinner and is considered as an alternative to that from adult animals. Here, the structures of adult and neonatal bovine pericardium tissues fixed with glutaraldehyde are characterized by synchrotron-based sma...
متن کاملOctanediol treatment of glutaraldehyde fixed bovine pericardium: evidence of anticalcification efficacy in the subcutaneous rat model.
OBJECTIVE Anticalcification strategies of glutaraldehyde-fixed xenograft tissue aim to extract lipids or to neutralize toxic aldehyde residuals. The purpose of this study was to evaluate the efficacy of octanediol compared to standard treatments of glutaraldehyde-fixed bovine pericardium in the subdermal rat model. Octanediol treatment is an ethanolic solution (40%) containing a long chain alip...
متن کاملEffects of gamma irradiation on mechanical behavior and calcification of glutaraldehyde-fixed bovine pericardium.
OBJECTIVE To evaluate the effect of gamma irradiation on glutaraldehyde-fixed bovine pericardium. METHOD Glutaraldehyde-fixed bovine pericardium was exposed to gamma radiation (doses from 0 to 10000 Gy). Six samples from each of nine groups were evaluated by optic microscopy, and shrinking and mechanical tests and the denaturation temperature was determined. Additionally, they were subcutaneo...
متن کاملAnti-calcifying treatment of glutaraldehyde fixed bovine pericardium: comparisons and evaluation of possible synergic effects
Objective: To evaluate a possible synergic effect of the most promising anti-calcifying agents investigated in the literature by sequential treatment. Method: Glutaraldehyde-fixed bovine pericardium was treated by: heating to 50o C, 80% ether, 0.125% chitosan, heparin, NaBH4 and 4% formaldehyde. Samples were evaluated by optic microscopy, shrinking and mechanical tests and implanted subcutaneou...
متن کاملValved Conduit with Glutaraldehyde-Fixed Bovine Pericardium Treated by Anticalcification Protocol
BACKGROUND A preclinical study was conducted for evaluating a valved conduit manufactured with a glutaraldehyde (GA)-fixed bovine pericardium treated using an anticalcification protocol. METHODS Bovine pericardia were decellularized, fixed with GA in an organic solvent, and detoxified. We prepared a valved conduit using these bovine pericardia and a specially designed mold. The valved conduit...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2014
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2014/189197